4-Amino-3,5-dichloroacetophenone | 37148-48-4

4-Amino-3,5-dichloroacetophenone Chemical Properties,Uses,Production

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Description

 4-Amino-3,5-dichloroacetophenone is an intermediate in the synthesis of the antitussive and antiasthmatic drug gramtin.

Storage

4-Amino-3,5-dichloroacetophenone should be stored in a cool, dry place in a small, well filled, well-closed container, protected from light. When a partially filled container is used, the air should be replaced by nitrogen or another inert gas.
4-Amino-3,5-dichloroacetophenone oxidizes on exposure to air, resulting in an increase in the peroxide value.

Chemical Properties

4-Amino-3,5-dichloroacetophenone is a white to light yellow crystal powder. Insoluble in cold water, slightly soluble in hot water.

Uses

4-Amino-3,5-dichloroacetophenone is used to synthesize the drug Clenbuterol. Clenbuterol is a steroid-like chemical that was initially developed to treat asthma in horses, working by relaxing the airways in the animals'lungs.

Application

4-Amino-3,5-dichloroacetophenone is a compound useful in organic synthesis.

Preparation

4-Amino-3,5-dichloroacetophenone was synthesized by chlorination of 4-aminoacetophenone. Add 4-aminoacetophenone and acetic acid (80%) into the reaction pot, stir and dissolve, quickly add chlorine-containing glacial acetic acid solution, the temperature of the addition is 5°C. After the addition is completed, immediately put into ice water to precipitate, filter, and wash with water to obtain the crude product. Recrystallize with ethanol to obtain the finished product of 4-Amino-3,5-dichloroacetophenone.

Application

4-Amino-3,5-dichloroacetophenone has active chemical properties and has been widely used in industrial chemistry, agricultural chemistry, and pharmaceutical chemistry. As a selective oxidant and green coupling reagent, it participates in a variety of oxidation reactions, rearrangement reactions, and amination reactions. In industry, it can also be used as a raw material for the synthesis of drugs, disinfectants, dyes, food seasonings, adhesives, explosives, etc.

Basic Info.

CAS

37148-48-4

Mf

C8h7cl2no

Purity

99% Min

Appearance

White to Almost White Powder

Application

Pharmaceutical Intermediates

Deliverytime

24 Hours After Payment Confirmation

Productioncapacity

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How to Choose 4-amino-3 5-dichloroacetophenone manufacturer?

20 Metric Ton/Month

Storage

Store in Dry, Dark and Ventilated Place

Flash Pointimpurity

Less Than 2.0%

Transport Package

Foil Bag

Specification

gram

Origin

China

Product Description

 

Company Profile

 

 

 

Packaging & Shipping

FAQ

Q1: Do you offer free sample?

A: Of course, we will offer free sample if you pay shipping fees.

Q2: How to solve the quality problem?
A: We supply high quality products and quality issue near to zero. If it happens caused by occasional?case, we will reship again or compensate customer loss, but customer need show us the evidence of problems or test report.

Q3: Whether transportation is safe and whether to reship if seized?
A: Yes, we offer almost 100% Shipping line with safe delivery. If seized unfortunately, we will ship and I am sure no custom issue.

Q4: ETA ?
A: Pack sent out in 2-3 days and offer tracking numbers after payment. ETA not the same decide by destination country. Please contact us for details (always 10-15 days).

Q5: Do you have any discount?
A: The price is negotiable. Plz shoot us your order content, we will quote a fair price.

Q6: What is your minimum order ?
A: Usually MOQ is 100g. But depends on the items and your requirements, we also can support small quantity, such as 20g and 50g.

Q7: How to order?
A: E-mail or message us that includes your order like format below:
product A ? 100g
product B ? 10vials
delivery country:?
Our sales will quote a total cost includes shipping fees and each item fees in 12 hours regularly.?
Our will satisfy your purchase and supply professional guide.

A: Of course, we will offer free sample if you pay shipping fees.A: We supply high quality products and quality issue near to zero. If it happens caused by occasional?case, we will reship again or compensate customer loss, but customer need show us the evidence of problems or test report.A: Yes, we offer almost 100% Shipping line with safe delivery. If seized unfortunately, we will ship and I am sure no custom issue.A: Pack sent out in 2-3 days and offer tracking numbers after payment. ETA not the same decide by destination country. Please contact us for details (always 10-15 days).A: The price is negotiable. Plz shoot us your order content, we will quote a fair price.A: Usually MOQ is 100g. But depends on the items and your requirements, we also can support small quantity, such as 20g and 50g.A: E-mail or message us that includes your order like format below:product A ? 100gproduct B ? 10vialsdelivery country:?Our sales will quote a total cost includes shipping fees and each item fees in 12 hours regularly.?Our will satisfy your purchase and supply professional guide.

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